Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes

The neuroinflammatory hypothesis of major depressive disorder is supported by several main findings. First, in humans and animals, activation of the immune system causes sickness behaviors that present during a major depressive episode (MDE), such as low mood, anhedonia, anorexia, and weight loss. S...

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Veröffentlicht in:	JAMA psychiatry (Chicago, Ill.) Jg. 72; H. 3; S. 268
Hauptverfasser:	Setiawan, Elaine, Wilson, Alan A, Mizrahi, Romina, Rusjan, Pablo M, Miler, Laura, Rajkowska, Grazyna, Suridjan, Ivonne, Kennedy, James L, Rekkas, P Vivien, Houle, Sylvain, Meyer, Jeffrey H
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.2015
Schlagworte:	Adult Anilides Biomarkers - metabolism Case-Control Studies Cerebral Cortex - metabolism Depressive Disorder, Major - metabolism Female Gyrus Cinguli - metabolism Humans Inflammation - metabolism Male Microglia - metabolism Middle Aged Positron-Emission Tomography - methods Prefrontal Cortex - metabolism Pyridines Receptors, GABA - metabolism Severity of Illness Index
ISSN:	2168-6238, 2168-6238
Online-Zugang:	Weitere Angaben
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