Amplicon Sequence Variants Artificially Split Bacterial Genomes into Separate Clusters

16S rRNA gene sequencing has engendered significant interest in studying microbial communities. There has been tension between trying to classify 16S rRNA gene sequences to increasingly lower taxonomic levels and the reality that those levels were defined using more sequence and physiological inform...

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Bibliographic Details
Published in:	mSphere Vol. 6; no. 4; p. e0019121
Main Author:	Schloss, Patrick D.
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 25.08.2021
Subjects:	Bacteria - classification Bacteria - genetics DNA, Bacterial - genetics Genetic Variation Genome, Bacterial High-Throughput Nucleotide Sequencing Human Microbiome Microbiota - genetics Observation Phylogeny RNA, Ribosomal, 16S - genetics Sequence Analysis, DNA OTU ASV bioinformatics microbial communities microbial ecology microbiome 16S rRNA gene
ISSN:	2379-5042, 2379-5042
Online Access:	Get full text
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