Inactivation of SARS-CoV-2 in the Liquid Phase: Are Aqueous Hydrogen Peroxide and Sodium Percarbonate Efficient Decontamination Agents?
A diluted 3% w/w hydrogen peroxide solution acidified to pH 2.5 by adding citric acid inactivated SARS-CoV-2 virus by more than 4 orders of magnitude in 5 min. After a contact time of 15 min, no viral replication was detected. Aqueous solutions of sodium percarbonate inactivated coronavirus by >3...
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| Published in: | ACS Chemical Health & Safety. Vol. 28; no. 4; p. 260 |
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| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
26.07.2021
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| ISSN: | 1878-0504, 1878-0504 |
| Online Access: | Get more information |
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| Summary: | A diluted 3% w/w hydrogen peroxide solution acidified to pH 2.5 by adding citric acid inactivated SARS-CoV-2 virus by more than 4 orders of magnitude in 5 min. After a contact time of 15 min, no viral replication was detected. Aqueous solutions of sodium percarbonate inactivated coronavirus by >3 log
diminution in 15 min. Conversely, H
O
solutions with no additives displayed a scarce virucidal activity (1.1 log
diminution in 5 min), confirming that a pH-modifying ingredient is necessary to have a H
O
-based disinfectant active against the novel coronavirus. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1878-0504 1878-0504 |
| DOI: | 10.1021/acs.chas.0c00095 |