A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants

Certain copy number variants (CNVs) greatly increase the risk of autism. The authors conducted a genetics-first study to investigate whether heterogeneity in the clinical presentation of autism is underpinned by specific genotype-phenotype relationships. This international study included 547 individ...

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Veröffentlicht in:	The American journal of psychiatry Jg. 178; H. 1; S. 77
Hauptverfasser:	Chawner, Samuel J R A, Doherty, Joanne L, Anney, Richard J L, Antshel, Kevin M, Bearden, Carrie E, Bernier, Raphael, Chung, Wendy K, Clements, Caitlin C, Curran, Sarah R, Cuturilo, Goran, Fiksinski, Ania M, Gallagher, Louise, Goin-Kochel, Robin P, Gur, Raquel E, Hanson, Ellen, Jacquemont, Sebastien, Kates, Wendy R, Kushan, Leila, Maillard, Anne M, McDonald-McGinn, Donna M, Mihaljevic, Marina, Miller, Judith S, Moss, Hayley, Pejovic-Milovancevic, Milica, Schultz, Robert T, Green-Snyder, LeeAnne, Vorstman, Jacob A, Wenger, Tara L, Hall, Jeremy, Owen, Michael J, van den Bree, Marianne B M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.01.2021
Schlagworte:	Autistic Disorder - diagnosis Autistic Disorder - epidemiology Autistic Disorder - genetics Child DNA Copy Number Variations - genetics Gene Deletion Genetic Association Studies Genetic Predisposition to Disease - genetics Heterozygote Humans Interview, Psychological Male Prevalence Risk Factors Severity of Illness Index Copy Number Variants Autism Genetics
ISSN:	1535-7228, 1535-7228
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