Human Listeriosis
Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause severe invasive infections upon ingestion with contaminated food. Clinically, listerial disease, or listeriosis, most often presents as bacteremia, meningitis or meningoencephalitis, and pregnancy-associated...
Gespeichert in:
| Veröffentlicht in: | Clinical microbiology reviews Jg. 36; H. 1; S. e0006019 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
United States
23.03.2023
|
| Schlagworte: | |
| ISSN: | 1098-6618, 1098-6618 |
| Online-Zugang: | Weitere Angaben |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause severe invasive infections upon ingestion with contaminated food. Clinically, listerial disease, or listeriosis, most often presents as bacteremia, meningitis or meningoencephalitis, and pregnancy-associated infections manifesting as miscarriage or neonatal sepsis. Invasive listeriosis is life-threatening and a main cause of foodborne illness leading to hospital admissions in Western countries. Sources of contamination can be identified through international surveillance systems for foodborne bacteria and strains' genetic data sharing. Large-scale whole genome studies have increased our knowledge on the diversity and evolution of L. monocytogenes, while recent pathophysiological investigations have improved our mechanistic understanding of listeriosis. In this article, we present an overview of human listeriosis with particular focus on relevant features of the causative bacterium, epidemiology, risk groups, pathogenesis, clinical manifestations, and treatment and prevention. |
|---|---|
| AbstractList | Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause severe invasive infections upon ingestion with contaminated food. Clinically, listerial disease, or listeriosis, most often presents as bacteremia, meningitis or meningoencephalitis, and pregnancy-associated infections manifesting as miscarriage or neonatal sepsis. Invasive listeriosis is life-threatening and a main cause of foodborne illness leading to hospital admissions in Western countries. Sources of contamination can be identified through international surveillance systems for foodborne bacteria and strains' genetic data sharing. Large-scale whole genome studies have increased our knowledge on the diversity and evolution of L. monocytogenes, while recent pathophysiological investigations have improved our mechanistic understanding of listeriosis. In this article, we present an overview of human listeriosis with particular focus on relevant features of the causative bacterium, epidemiology, risk groups, pathogenesis, clinical manifestations, and treatment and prevention.Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause severe invasive infections upon ingestion with contaminated food. Clinically, listerial disease, or listeriosis, most often presents as bacteremia, meningitis or meningoencephalitis, and pregnancy-associated infections manifesting as miscarriage or neonatal sepsis. Invasive listeriosis is life-threatening and a main cause of foodborne illness leading to hospital admissions in Western countries. Sources of contamination can be identified through international surveillance systems for foodborne bacteria and strains' genetic data sharing. Large-scale whole genome studies have increased our knowledge on the diversity and evolution of L. monocytogenes, while recent pathophysiological investigations have improved our mechanistic understanding of listeriosis. In this article, we present an overview of human listeriosis with particular focus on relevant features of the causative bacterium, epidemiology, risk groups, pathogenesis, clinical manifestations, and treatment and prevention. Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause severe invasive infections upon ingestion with contaminated food. Clinically, listerial disease, or listeriosis, most often presents as bacteremia, meningitis or meningoencephalitis, and pregnancy-associated infections manifesting as miscarriage or neonatal sepsis. Invasive listeriosis is life-threatening and a main cause of foodborne illness leading to hospital admissions in Western countries. Sources of contamination can be identified through international surveillance systems for foodborne bacteria and strains' genetic data sharing. Large-scale whole genome studies have increased our knowledge on the diversity and evolution of L. monocytogenes, while recent pathophysiological investigations have improved our mechanistic understanding of listeriosis. In this article, we present an overview of human listeriosis with particular focus on relevant features of the causative bacterium, epidemiology, risk groups, pathogenesis, clinical manifestations, and treatment and prevention. |
| Author | Vázquez-Boland, José A Koopmans, Merel M Brouwer, Matthijs C van de Beek, Diederik |
| Author_xml | – sequence: 1 givenname: Merel M surname: Koopmans fullname: Koopmans, Merel M organization: Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam, the Netherlands – sequence: 2 givenname: Matthijs C surname: Brouwer fullname: Brouwer, Matthijs C organization: Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam, the Netherlands – sequence: 3 givenname: José A orcidid: 0000-0003-4521-5972 surname: Vázquez-Boland fullname: Vázquez-Boland, José A organization: Infection Medicine, Edinburgh Medical School (Biomedical Sciences), University of Edinburgh, Edinburgh, United Kingdom – sequence: 4 givenname: Diederik orcidid: 0000-0002-4571-044X surname: van de Beek fullname: van de Beek, Diederik organization: Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam, the Netherlands |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/36475874$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNjztLBDEURoOsuA8tBGuxtMmam-edUpbVFQZstB6SzA2MzGOdzBT-exFXsDpfcfjgrNmiH3pi7AbEFkDiQ-zGrRDCCg7FGVuBKJBbC7j4t5dsnfOHEKC1wgu2VFY7g06v2PVh7nx_VzZ5orEZcpMv2XnybaarEzfs_Wn_tjvw8vX5ZfdYcq_RTDyFZGVCk9B5iIDSWAhotRKkNKQC6kCYRG2ir2XUFA05pwL6EGvhjZQbdv_7exyHz5nyVHVNjtS2vqdhzpV0RinQUv6otyd1Dh3V1XFsOj9-VX8Z8htlp0li |
| CitedBy_id | crossref_primary_10_1155_cjid_5960643 crossref_primary_10_1099_jmm_0_001800 crossref_primary_10_1007_s11250_024_03934_y crossref_primary_10_1155_2024_8891963 crossref_primary_10_1016_j_foodcont_2025_111583 crossref_primary_10_1186_s13613_023_01218_6 crossref_primary_10_3390_biology14050495 crossref_primary_10_1093_femsre_fuad037 crossref_primary_10_1089_fpd_2023_0046 crossref_primary_10_1128_mbio_01183_25 crossref_primary_10_3389_fcimb_2025_1612628 crossref_primary_10_3389_fmicb_2025_1614697 crossref_primary_10_1002_pmic_70034 crossref_primary_10_3934_agrfood_2025006 crossref_primary_10_1016_j_jfp_2024_100322 crossref_primary_10_1186_s12884_025_07315_7 crossref_primary_10_1089_fpd_2023_0163 crossref_primary_10_3389_fmicb_2024_1425437 crossref_primary_10_3390_microorganisms11082024 crossref_primary_10_3390_app131810257 crossref_primary_10_3390_pathogens12030444 crossref_primary_10_1016_j_ijfoodmicro_2023_110479 crossref_primary_10_5114_pjr_189214 crossref_primary_10_3390_foods14071266 crossref_primary_10_1021_acs_jafc_5c03223 crossref_primary_10_1016_j_fm_2024_104649 crossref_primary_10_1128_spectrum_03244_23 crossref_primary_10_1007_s10068_025_01849_4 crossref_primary_10_3201_eid2910_230746 crossref_primary_10_1099_mgen_0_001397 crossref_primary_10_2147_JIR_S535302 crossref_primary_10_1111_1471_0307_13045 crossref_primary_10_1111_mmi_15349 crossref_primary_10_3389_fcimb_2025_1542165 crossref_primary_10_1016_j_molimm_2025_04_006 crossref_primary_10_1186_s13054_025_05421_8 crossref_primary_10_3390_microbiolres16090195 crossref_primary_10_1016_j_foodres_2025_117537 crossref_primary_10_3390_microorganisms11112617 crossref_primary_10_1155_2024_7785327 crossref_primary_10_3389_fmicb_2025_1640990 crossref_primary_10_1128_mra_00180_25 crossref_primary_10_1038_s41598_025_99141_2 crossref_primary_10_1016_j_foodcont_2025_111485 crossref_primary_10_1016_j_micpath_2025_107600 crossref_primary_10_3389_fmed_2024_1381262 crossref_primary_10_1186_s12985_025_02706_w crossref_primary_10_14202_vetworld_2025_1899_1910 crossref_primary_10_1186_s13073_024_01379_4 crossref_primary_10_1542_neo_26_9_052 crossref_primary_10_3390_foods13162495 crossref_primary_10_1016_j_foodcont_2024_110711 crossref_primary_10_1128_aem_00067_25 crossref_primary_10_1016_j_ijbiomac_2025_143113 crossref_primary_10_3390_app15116109 crossref_primary_10_1016_j_foodcont_2025_111499 crossref_primary_10_3390_antibiotics13020181 crossref_primary_10_1016_S1473_3099_24_00182_8 crossref_primary_10_22627_2072_8107_2025_24_2_65_72 crossref_primary_10_3390_foods13091364 crossref_primary_10_3390_pathogens12060837 crossref_primary_10_1089_fpd_2024_0156 crossref_primary_10_7717_peerj_19126 crossref_primary_10_3389_fmicb_2025_1616720 crossref_primary_10_1080_17460913_2025_2459530 crossref_primary_10_1128_msystems_00587_25 crossref_primary_10_1371_journal_pgen_1011621 crossref_primary_10_3390_antibiotics14030236 crossref_primary_10_1016_j_fm_2024_104550 crossref_primary_10_1038_s41467_024_54459_9 crossref_primary_10_7759_cureus_87792 crossref_primary_10_1016_j_foodcont_2024_111118 crossref_primary_10_2147_IDR_S508470 crossref_primary_10_2478_am_2024_0005 crossref_primary_10_3390_fermentation11060343 crossref_primary_10_1016_j_ijbiomac_2025_140908 crossref_primary_10_1007_s00003_025_01546_8 crossref_primary_10_1038_s41597_024_03440_8 crossref_primary_10_2147_IDR_S431402 crossref_primary_10_3389_fimmu_2023_1295523 crossref_primary_10_1016_S1877_7856_25_49258_7 crossref_primary_10_1097_MCC_0000000000001087 crossref_primary_10_1016_j_ijfoodmicro_2024_110959 crossref_primary_10_1093_jambio_lxaf199 crossref_primary_10_1016_j_ijfoodmicro_2024_110954 crossref_primary_10_1016_j_chemosphere_2024_142706 crossref_primary_10_1016_j_ijfoodmicro_2024_110951 crossref_primary_10_1016_j_fm_2025_104745 crossref_primary_10_1016_j_jinf_2024_106254 crossref_primary_10_1016_j_jinf_2025_106552 crossref_primary_10_1097_FM9_0000000000000269 crossref_primary_10_3389_fcimb_2023_1287564 crossref_primary_10_1111_jfs_13055 crossref_primary_10_1016_j_freeradbiomed_2024_11_038 crossref_primary_10_2147_IDR_S446860 crossref_primary_10_1016_j_ijfoodmicro_2024_110826 crossref_primary_10_3389_fmed_2023_1322993 crossref_primary_10_1016_j_ajt_2024_02_025 crossref_primary_10_3390_cells13010088 crossref_primary_10_3390_microorganisms12051003 crossref_primary_10_4103_CIDS_CIDS_66_24 crossref_primary_10_3390_vetsci10050344 crossref_primary_10_1016_j_bios_2025_117835 crossref_primary_10_1515_jpm_2025_0214 crossref_primary_10_3928_19382359_20240908_07 crossref_primary_10_1002_imt2_196 crossref_primary_10_2903_j_efsa_2024_9106 crossref_primary_10_1002_advs_202406760 crossref_primary_10_3390_foods13193032 crossref_primary_10_3390_app15063101 crossref_primary_10_7759_cureus_92005 crossref_primary_10_3390_microorganisms12102102 crossref_primary_10_1016_j_jfp_2023_100147 crossref_primary_10_3390_antibiotics13060525 crossref_primary_10_1128_iai_00422_23 crossref_primary_10_3390_foods13182950 crossref_primary_10_1007_s40121_024_00986_3 crossref_primary_10_1099_mgen_0_001410 crossref_primary_10_1007_s10389_025_02435_y crossref_primary_10_3390_foods14020290 crossref_primary_10_2903_j_efsa_2023_8442 crossref_primary_10_3389_fmicb_2023_1268709 crossref_primary_10_1128_aem_01017_23 crossref_primary_10_1080_22221751_2024_2307520 crossref_primary_10_1016_j_micres_2024_127963 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1128/cmr.00060-19 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine Biology |
| EISSN | 1098-6618 |
| ExternalDocumentID | 36475874 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Review |
| GrantInformation_xml | – fundername: Wellcome Trust |
| GroupedDBID | --- 0R~ 18M 29B 2WC 39C 4.4 53G 5GY 5VS 6J9 AAGFI ACGFO ADBBV AENEX AGVNZ ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BTFSW CGR CS3 CUY CVF DIK DU5 E3Z EBS ECM EIF F5P FRP GX1 H13 HYE HZ~ KQ8 NPM O9- OK1 P2P RHI RNS RPM RSF TR2 W2D W8F WH7 WOQ 7X8 |
| ID | FETCH-LOGICAL-a485t-fbf62f85f87a1c182561b86430e341f91dbe8f0d5cad2c4ec5e773b8abcd0a522 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 158 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=00060-19&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1098-6618 |
| IngestDate | Fri Sep 05 14:34:27 EDT 2025 Mon Jul 21 05:37:46 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | epidemiology neurolisteriosis listeriosis pathophysiology Listeria monocytogenes bacterial genetics histopathology pregnancy-related listeriosis |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-a485t-fbf62f85f87a1c182561b86430e341f91dbe8f0d5cad2c4ec5e773b8abcd0a522 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0003-4521-5972 0000-0002-4571-044X |
| OpenAccessLink | https://pmc.ncbi.nlm.nih.gov/articles/PMC10035648/pdf/cmr.00060-19.pdf |
| PMID | 36475874 |
| PQID | 2753314222 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_2753314222 pubmed_primary_36475874 |
| PublicationCentury | 2000 |
| PublicationDate | 2023-03-23 |
| PublicationDateYYYYMMDD | 2023-03-23 |
| PublicationDate_xml | – month: 03 year: 2023 text: 2023-03-23 day: 23 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Clinical microbiology reviews |
| PublicationTitleAlternate | Clin Microbiol Rev |
| PublicationYear | 2023 |
| SSID | ssj0014438 |
| Score | 2.6903012 |
| SecondaryResourceType | review_article |
| Snippet | Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause severe invasive infections upon ingestion with contaminated food.... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | e0006019 |
| SubjectTerms | Bacteremia Female Food Microbiology Humans Infant, Newborn Listeria monocytogenes - genetics Listeriosis - epidemiology Listeriosis - microbiology Listeriosis - prevention & control Pregnancy Risk Factors |
| Title | Human Listeriosis |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/36475874 https://www.proquest.com/docview/2753314222 |
| Volume | 36 |
| WOSCitedRecordID | wos00060-19&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT8MwDLaAAeICY7zGS0PiGtYlKUlPCCEmDtu0A6DdquYl7bB2rAOJf4-TdtoNIXHJrVJiu_YX2_EHcItOj5lEayKccoQnhhGJUZlYZe6ps7HW4VXa-0CMRnIyScZ1wq2s2ypXPjE4alNonyPvUsTVLCQsHuYfxLNG-epqTaGxCQ2GUMZbtZisqwics-opXCIJxiG5anynsqtni7swjIT0fgGXIcj0D_67vSbs1_Cy81jZwyFs2LwFOxXh5HcLdod1Kf0ImiF93xl4NS-mRTktj-Gt__z69EJqfgSScRkvCUoX5SljJ0XW03hRQCykJEKMyGJscknPKCtdZGKdGaq51bEVgimZKW2iDIHXCWzlRW7PoIPXUYHK5JHi2s88U8LRJHKILZxzgro23KyOnaL9-aJCltvis0zXB2_DaSW7dF4Nykj9bPpYCn7-h68vYM8zufv2LsouoeHw77NXsK2_ltNycR0Ui-toPPwBrUqrsw |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Human+Listeriosis&rft.jtitle=Clinical+microbiology+reviews&rft.au=Koopmans%2C+Merel+M&rft.au=Brouwer%2C+Matthijs+C&rft.au=V%C3%A1zquez-Boland%2C+Jos%C3%A9+A&rft.au=van+de+Beek%2C+Diederik&rft.date=2023-03-23&rft.eissn=1098-6618&rft.volume=36&rft.issue=1&rft.spage=e0006019&rft_id=info:doi/10.1128%2Fcmr.00060-19&rft_id=info%3Apmid%2F36475874&rft_id=info%3Apmid%2F36475874&rft.externalDocID=36475874 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1098-6618&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1098-6618&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1098-6618&client=summon |