Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance

The management of infections due to Klebsiella pneumoniae has been complicated by the emergence of antimicrobial resistance, especially to carbapenems. Resistance to carbapenems in K. pneumoniae involves multiple mechanisms, including the production of carbapenemases (e.g., KPC, NDM, VIM, OXA-48-lik...

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Bibliographic Details
Published in:	Antimicrobial agents and chemotherapy Vol. 59; no. 10; p. 5873
Main Authors:	Pitout, Johann D D, Nordmann, Patrice, Poirel, Laurent
Format:	Journal Article
Language:	English
Published:	United States 01.10.2015
Subjects:	Anti-Bacterial Agents - pharmacology Bacterial Proteins - genetics Bacterial Proteins - metabolism beta-Lactam Resistance - genetics beta-Lactamases - genetics beta-Lactamases - metabolism Carbapenems - pharmacology Clone Cells Conjugation, Genetic Cross Infection - drug therapy Cross Infection - epidemiology Cross Infection - microbiology DNA Transposable Elements Gene Expression Regulation, Bacterial Humans Klebsiella Infections - drug therapy Klebsiella Infections - epidemiology Klebsiella Infections - microbiology Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - enzymology Klebsiella pneumoniae - genetics Klebsiella pneumoniae - pathogenicity Plasmids - chemistry Plasmids - metabolism Porins - deficiency Porins - genetics Recombination, Genetic
ISSN:	1098-6596, 1098-6596
Online Access:	Get more information
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