Loss of Neutrophil Homing to the Periodontal Tissues Modulates the Composition and Disease Potential of the Oral Microbiota

Periodontal disease is considered to arise from an imbalance in the interplay between the host and its commensal microbiota, characterized by inflammation, destructive periodontal bone loss, and a dysbiotic oral microbial community. The neutrophil is a key component of defense of the periodontium: d...

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Bibliographic Details
Published in:	Infection and immunity Vol. 89; no. 12; p. e0030921
Main Authors:	Hashim, A, Alsam, A, Payne, M A, Aduse-Opoku, J, Curtis, M A, Joseph, S
Format:	Journal Article
Language:	English
Published:	United States 16.11.2021
Subjects:	Animals Biomarkers Disease Models, Animal Disease Susceptibility Dysbiosis Mice Mice, Knockout Microbiota Neutrophil Infiltration Neutrophils - physiology Periodontal Diseases - etiology Periodontal Diseases - metabolism Periodontal Diseases - pathology Periodontitis - etiology Periodontitis - metabolism Periodontitis - pathology Receptors, Interleukin-8B - genetics Receptors, Interleukin-8B - metabolism CXCR2 periodontitis oral microbiology oral microbiome neutrophils bone loss dysbiosis
ISSN:	1098-5522, 1098-5522
Online Access:	Get more information
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