Proteolysis Targeting Chimeras (PROTACs): A Perspective on Integral Membrane Protein Degradation

Targeted protein degradation (TPD) is a promising therapeutic modality to modulate protein levels and its application promises to reduce the "undruggable" proteome. Among TPD strategies, Proteolysis TArgeting Chimera (PROTAC) technology has shown a tremendous potential with attractive adva...

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Bibliographic Details
Published in:ACS pharmacology & translational science Vol. 5; no. 10; p. 849
Main Authors: Ruffilli, Camilla, Roth, Sascha, Rodrigo, Monica, Boyd, Helen, Zelcer, Noam, Moreau, Kevin
Format: Journal Article
Language:English
Published: 14.10.2022
ISSN:2575-9108, 2575-9108
Online Access:Get more information
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