Drug side-effect prediction based on the integration of chemical and biological spaces

Drug side-effects, or adverse drug reactions, have become a major public health concern and remain one of the main causes of drug failure and of drug withdrawal once they have reached the market. Therefore, the identification of potential severe side-effects is a challenging issue. In this paper, we...

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Veröffentlicht in:	Journal of chemical information and modeling Jg. 52; H. 12; S. 3284
Hauptverfasser:	Yamanishi, Yoshihiro, Pauwels, Edouard, Kotera, Masaaki
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 21.12.2012
Schlagworte:	Computational Biology - methods Drug-Related Side Effects and Adverse Reactions Models, Molecular Protein Conformation Proteins - chemistry Proteins - metabolism
ISSN:	1549-960X, 1549-960X
Online-Zugang:	Weitere Angaben
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