Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples

Early and accurate in vivo diagnosis of Creutzfeldt-Jakob disease (CJD) is necessary for quickly distinguishing treatable from untreatable rapidly progressive dementias and for future therapeutic trials. This early diagnosis is becoming possible using the real-time quaking-induced conversion (RT-QuI...

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Vydané v:	JAMA neurology Ročník 74; číslo 2; s. 155
Hlavní autori:	Bongianni, Matilde, Orrù, Christina, Groveman, Bradley R, Sacchetto, Luca, Fiorini, Michele, Tonoli, Giovanni, Triva, Giorgio, Capaldi, Stefano, Testi, Silvia, Ferrari, Sergio, Cagnin, Annachiara, Ladogana, Anna, Poleggi, Anna, Colaizzo, Elisa, Tiple, Dorina, Vaianella, Luana, Castriciano, Santina, Marchioni, Daniele, Hughson, Andrew G, Imperiale, Daniele, Cattaruzza, Tatiana, Fabrizi, Gian Maria, Pocchiari, Maurizio, Monaco, Salvatore, Caughey, Byron, Zanusso, Gianluigi
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.02.2017
Predmet:	Aged Algorithms Case-Control Studies Creutzfeldt-Jakob Syndrome - cerebrospinal fluid Creutzfeldt-Jakob Syndrome - diagnosis Creutzfeldt-Jakob Syndrome - pathology Female Humans Italy Male Middle Aged Olfactory Mucosa - metabolism Olfactory Mucosa - pathology Prions - cerebrospinal fluid Sensitivity and Specificity
ISSN:	2168-6157, 2168-6157
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