In situ Sensing of Single Binding Events by Localized Surface Plasmon Resonance

Single binding events of nanoparticle-labeled DNA strands were detected as stepwise peak shifts in localized surface plasmon resonance by single particle measurement. We confirmed the number of binding events by observing label particles by scanning electron microscopy. Our simulation based on a mul...

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Bibliographic Details
Published in:	Nano letters Vol. 8; no. 10; pp. 3450 - 3455
Main Authors:	Sannomiya, Takumi, Hafner, Christian, Voros, Janos
Format:	Journal Article
Language:	English
Published:	Washington, DC American Chemical Society 01.10.2008
Subjects:	Adsorption Biocompatible Materials - chemistry Biosensing Techniques Computer Simulation Condensed matter: electronic structure, electrical, magnetic, and optical properties Cross-disciplinary physics: materials science; rheology DNA - chemistry Electron states and collective excitations in thin films, multilayers, quantum wells, mesoscopic and nanoscale systems Electronic structure and electrical properties of surfaces, interfaces, thin films and low-dimensional structures Equipment Design Exact sciences and technology Kinetics Materials science Metal Nanoparticles - chemistry Microscopy, Electron, Scanning Nanocrystalline materials Nanoscale materials and structures: fabrication and characterization Nanotechnology - methods Physics Polyethylene Glycols - chemistry Polylysine - chemistry Surface Plasmon Resonance - instrumentation Surface Plasmon Resonance - methods Nanoparticles Scanning electron microscopy DNA Digital simulation Surface plasmon resonance Gallium phosphide Nanostructured materials
ISSN:	1530-6984, 1530-6992
Online Access:	Get full text
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