Fluorinating the Sugar and the Nucleotide: Exploring Fluorination Within GDP-Mannose Probes Using Chemoenzymatic Synthesis

Fluorinated glycans offer a prime opportunity to study the intricacies of their associated binding events with proteins, invoke resistance toward enzymatic hydrolysis, and modulate carbohydrate physicochemical properties. Sugar nucleotides are the key building blocks used by glycosyltransferases and...

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Vydané v:	JACS Au Ročník 5; číslo 8; s. 3994 - 4001
Hlavní autori:	Dolan, Jonathan P., Evans, Sean T., Benckendorff, Caecilie M. M., Sari, Suat, Ní Cheallaigh, Aisling, Miller, Gavin J.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States American Chemical Society 25.08.2025
Predmet:	fluorination chemical probe glycan sugar nucleotide dehydrogenase
ISSN:	2691-3704, 2691-3704
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