Parallel Nanometric 3D Tracking of Intracellular Gold Nanorods Using Multifocal Two-Photon Microscopy
We report a novel technique for long-term parallel three dimensional (3D)-tracking of gold nanorods in live cells with nanometer resolution. Gold nanorods feature a strong plasmon-enhanced two-photon luminescence, can be easily functionalized, and have been shown to be nontoxic. These properties mak...
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| Vydané v: | Nano letters Ročník 13; číslo 3; s. 980 - 986 |
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| Hlavní autori: | , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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Washington, DC
American Chemical Society
13.03.2013
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| ISSN: | 1530-6984, 1530-6992, 1530-6992 |
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| Abstract | We report a novel technique for long-term parallel three dimensional (3D)-tracking of gold nanorods in live cells with nanometer resolution. Gold nanorods feature a strong plasmon-enhanced two-photon luminescence, can be easily functionalized, and have been shown to be nontoxic. These properties make gold nanorods very suitable for in vivo two-photon luminescence microscopy. By rapid multifocal scanning, we combine the advantages of 3D molecular tracking methods using wide-field imaging with the advantages of two-photon microscopy. Isolated gold nanorods can be localized with a resolution of 4 nm in the xy-plane and 8 nm in the z-direction. The polarization-dependence of the two-photon luminescence signal can be used to resolve the angular orientation, even when two gold nanorods are separated by less than the diffraction limit. Individual nanorods in live U2OS cells could be followed in 3 dimensions for over 30 min, with a photon noise limited accuracy, and a time resolution of 50 ms in 2D and 500 ms in 3D. |
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| AbstractList | We report a novel technique for long-term parallel three dimensional (3D)-tracking of gold nanorods in live cells with nanometer resolution. Gold nanorods feature a strong plasmon-enhanced two-photon luminescence, can be easily functionalized, and have been shown to be nontoxic. These properties make gold nanorods very suitable for in vivo two-photon luminescence microscopy. By rapid multifocal scanning, we combine the advantages of 3D molecular tracking methods using wide-field imaging with the advantages of two-photon microscopy. Isolated gold nanorods can be localized with a resolution of 4 nm in the xy-plane and 8 nm in the z-direction. The polarization-dependence of the two-photon luminescence signal can be used to resolve the angular orientation, even when two gold nanorods are separated by less than the diffraction limit. Individual nanorods in live U2OS cells could be followed in 3 dimensions for over 30 min, with a photon noise limited accuracy, and a time resolution of 50 ms in 2D and 500 ms in 3D.We report a novel technique for long-term parallel three dimensional (3D)-tracking of gold nanorods in live cells with nanometer resolution. Gold nanorods feature a strong plasmon-enhanced two-photon luminescence, can be easily functionalized, and have been shown to be nontoxic. These properties make gold nanorods very suitable for in vivo two-photon luminescence microscopy. By rapid multifocal scanning, we combine the advantages of 3D molecular tracking methods using wide-field imaging with the advantages of two-photon microscopy. Isolated gold nanorods can be localized with a resolution of 4 nm in the xy-plane and 8 nm in the z-direction. The polarization-dependence of the two-photon luminescence signal can be used to resolve the angular orientation, even when two gold nanorods are separated by less than the diffraction limit. Individual nanorods in live U2OS cells could be followed in 3 dimensions for over 30 min, with a photon noise limited accuracy, and a time resolution of 50 ms in 2D and 500 ms in 3D. We report a novel technique for long-term parallel three dimensional (3D)-tracking of gold nanorods in live cells with nanometer resolution. Gold nanorods feature a strong plasmon-enhanced two-photon luminescence, can be easily functionalized, and have been shown to be nontoxic. These properties make gold nanorods very suitable for in vivo two-photon luminescence microscopy. By rapid multifocal scanning, we combine the advantages of 3D molecular tracking methods using wide-field imaging with the advantages of two-photon microscopy. Isolated gold nanorods can be localized with a resolution of 4 nm in the xy-plane and 8 nm in the z-direction. The polarization-dependence of the two-photon luminescence signal can be used to resolve the angular orientation, even when two gold nanorods are separated by less than the diffraction limit. Individual nanorods in live U2OS cells could be followed in 3 dimensions for over 30 min, with a photon noise limited accuracy, and a time resolution of 50 ms in 2D and 500 ms in 3D. |
| Author | Ashcroft, Brian van den Broek, Bram Oosterkamp, Tjerk H van Noort, John |
| AuthorAffiliation | Leiden University |
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| Cites_doi | 10.1021/nl201225r 10.1021/ja106506k 10.1364/OE.14.003406 10.1039/b901782h 10.1021/nl072377+ 10.1529/biophysj.108.140392 10.1088/0022-3727/41/18/185501 10.1364/OE.17.011350 10.1002/smll.200700595 10.1021/jp1040663 10.1073/pnas.0504892102 10.1364/OL.31.002018 10.1021/nl3010918 10.1529/biophysj.104.044230 10.1021/jp990183f 10.1242/jcs.02300 10.1021/nl0709120 10.1103/PhysRevLett.107.037401 10.1038/nmat1390 10.1038/nmeth989 10.1021/nl070363y 10.1046/j.1365-2818.1998.00431.x 10.3389/neuro.04.005.2008 10.1016/S0006-3495(01)76173-5 10.1021/jp9831482 10.1073/pnas.93.7.2926 10.1021/la062642r 10.1111/j.1600-0854.2009.00902.x 10.1021/jp056360w 10.1126/science.1104274 10.1073/pnas.0610081104 10.1016/S0006-3495(02)75618-X 10.1021/nl062962v 10.1152/jn.00865.2005 10.1021/nl802053h 10.1038/nmeth.1444 10.1126/science.1073765 10.1073/pnas.0810636105 10.1364/OL.28.001918 10.1063/1.2437066 10.1007/s00216-008-2410-4 |
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| Keywords | two-photon imaging Gold nanorods single-particle tracking nanometry In vivo Gold Time resolution Tracking Imaging Optical properties Luminescence Plasmons Nanorod Nanostructured materials Time resolved spectra |
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| References | Piyawattanametha W. (ref40/cit40) 2006; 31 Boyer D. (ref17/cit17) 2002; 297 Wang D.-S. (ref9/cit9) 2009; 17 Nanorods A. G. (ref12/cit12) 2007; 7 Hopt A. (ref22/cit22) 2001; 80 Ruijgrok P. (ref34/cit34) 2011; 107 Link S. (ref23/cit23) 1999; 103 Moerner W. E. (ref1/cit1) 2007; 104 Lommerse P. H. M. (ref4/cit4) 2005; 118 Helmchen F. (ref20/cit20) 2007; 4 Ram S. (ref29/cit29) 2008; 95 Michalet X. (ref5/cit5) 2005; 307 Pinaud F. (ref6/cit6) 2010; 7 Jureller J. E. (ref18/cit18) 2006; 14 Medintz I. L. (ref7/cit7) 2005; 4 ref14/cit14 Wang G. (ref16/cit16) 2010; 132 Wang H. (ref10/cit10) 2005; 102 Zhang R. (ref19/cit19) 2011; 11 Sacconi L. (ref101/cit101) 2003; 28 Ekici O. (ref27/cit27) 2008; 41 Nikolenko V. (ref39/cit39) 2008; 2 Pinaud F. (ref8/cit8) 2009; 10 Mohamed M. B. (ref25/cit25) 1998; 102 Huff T. B. (ref100/cit100) 2007; 23 Chithrani B. D. (ref31/cit31) 2007; 7 Holtzer L. (ref28/cit28) 2007; 90 Durr N. J. (ref11/cit11) 2007; 7 Nan X. (ref32/cit32) 2005; 109 Vaziri A. (ref41/cit41) 2008; 105 Toprak E. (ref37/cit37) 2007; 7 Anderson L. J. E. (ref15/cit15) 2010; 114 Shaner N. C. (ref3/cit3) 2005; 2 Schmidt T. (ref2/cit2) 1996; 93 Liu Y. (ref26/cit26) 2009; 19 Ma H. (ref35/cit35) 2012; 12 Iyer V. (ref38/cit38) 2006; 95 Selhuber-Unkel C. (ref33/cit33) 2008; 8 Delehanty J. B. (ref36/cit36) 2009; 393 Squier J. (ref21/cit21) 1998; 192 Thompson R. E. (ref24/cit24) 2002; 82 Lewinski N. (ref13/cit13) 2008; 4 Levi V. (ref30/cit30) 2005; 88 |
| References_xml | – volume: 11 start-page: 4074 year: 2011 ident: ref19/cit19 publication-title: Nano Lett. doi: 10.1021/nl201225r – volume: 132 start-page: 16417 year: 2010 ident: ref16/cit16 publication-title: J. Am. Chem. Soc. doi: 10.1021/ja106506k – ident: ref14/cit14 – volume: 14 start-page: 12482 year: 2006 ident: ref18/cit18 publication-title: Opt. Express doi: 10.1364/OE.14.003406 – volume: 19 start-page: 2704 year: 2009 ident: ref26/cit26 publication-title: J. Mater. Chem. doi: 10.1039/b901782h – volume: 7 start-page: 3808 year: 2007 ident: ref12/cit12 publication-title: Nano Lett. doi: 10.1021/nl072377+ – volume: 95 start-page: 6025 year: 2008 ident: ref29/cit29 publication-title: Biophys. J. doi: 10.1529/biophysj.108.140392 – volume: 41 start-page: 185501 year: 2008 ident: ref27/cit27 publication-title: J. Phys. D: Appl. Phys. doi: 10.1088/0022-3727/41/18/185501 – volume: 17 start-page: 11350 year: 2009 ident: ref9/cit9 publication-title: Opt. Express doi: 10.1364/OE.17.011350 – volume: 4 start-page: 26 year: 2008 ident: ref13/cit13 publication-title: Small doi: 10.1002/smll.200700595 – volume: 114 start-page: 11127 year: 2010 ident: ref15/cit15 publication-title: J. Phys. Chem. C doi: 10.1021/jp1040663 – volume: 102 start-page: 15752 year: 2005 ident: ref10/cit10 publication-title: Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.0504892102 – volume: 31 start-page: 2018 year: 2006 ident: ref40/cit40 publication-title: Opt. Lett. doi: 10.1364/OL.31.002018 – volume: 12 start-page: 3954 year: 2012 ident: ref35/cit35 publication-title: Nano Lett. doi: 10.1021/nl3010918 – volume: 88 start-page: 2919 year: 2005 ident: ref30/cit30 publication-title: Biophys. J. doi: 10.1529/biophysj.104.044230 – volume: 103 start-page: 3073 year: 1999 ident: ref23/cit23 publication-title: J. Phys. Chem. B doi: 10.1021/jp990183f – volume: 118 start-page: 1799 year: 2005 ident: ref4/cit4 publication-title: J. Cell Sci. doi: 10.1242/jcs.02300 – volume: 7 start-page: 2043 year: 2007 ident: ref37/cit37 publication-title: Nano Lett. doi: 10.1021/nl0709120 – volume: 2 start-page: 905 year: 2005 ident: ref3/cit3 publication-title: Nat. Mater. – volume: 107 start-page: 1 year: 2011 ident: ref34/cit34 publication-title: Phys. Rev. Lett. doi: 10.1103/PhysRevLett.107.037401 – volume: 4 start-page: 435 year: 2005 ident: ref7/cit7 publication-title: Nat. Mater. doi: 10.1038/nmat1390 – volume: 4 start-page: 73 year: 2007 ident: ref20/cit20 publication-title: Nat. Methods doi: 10.1038/nmeth989 – volume: 7 start-page: 1542 year: 2007 ident: ref31/cit31 publication-title: Nano Lett. doi: 10.1021/nl070363y – volume: 192 start-page: 217 year: 1998 ident: ref21/cit21 publication-title: J. Microsc. doi: 10.1046/j.1365-2818.1998.00431.x – volume: 2 start-page: 5 year: 2008 ident: ref39/cit39 publication-title: Front. Neural Circuits doi: 10.3389/neuro.04.005.2008 – volume: 80 start-page: 2029 year: 2001 ident: ref22/cit22 publication-title: Biophys. J. doi: 10.1016/S0006-3495(01)76173-5 – volume: 102 start-page: 9370 year: 1998 ident: ref25/cit25 publication-title: J. Phys. Chem. B doi: 10.1021/jp9831482 – volume: 93 start-page: 2926 year: 1996 ident: ref2/cit2 publication-title: Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.93.7.2926 – volume: 23 start-page: 1596 year: 2007 ident: ref100/cit100 publication-title: Langmuir doi: 10.1021/la062642r – volume: 10 start-page: 691 year: 2009 ident: ref8/cit8 publication-title: Traffic (Copenhagen, Denmark) doi: 10.1111/j.1600-0854.2009.00902.x – volume: 109 start-page: 24220 year: 2005 ident: ref32/cit32 publication-title: J. Phys. Chem. B doi: 10.1021/jp056360w – volume: 307 start-page: 538 year: 2005 ident: ref5/cit5 publication-title: Science (New York, N.Y.) doi: 10.1126/science.1104274 – volume: 104 start-page: 12596 year: 2007 ident: ref1/cit1 publication-title: Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.0610081104 – volume: 82 start-page: 2775 year: 2002 ident: ref24/cit24 publication-title: Biophys. J. doi: 10.1016/S0006-3495(02)75618-X – volume: 7 start-page: 941 year: 2007 ident: ref11/cit11 publication-title: Nano Lett. doi: 10.1021/nl062962v – volume: 95 start-page: 535 year: 2006 ident: ref38/cit38 publication-title: J. Neurophysiol. doi: 10.1152/jn.00865.2005 – volume: 8 start-page: 2998 year: 2008 ident: ref33/cit33 publication-title: Nano Lett. doi: 10.1021/nl802053h – volume: 7 start-page: 275 year: 2010 ident: ref6/cit6 publication-title: Nat. Methods doi: 10.1038/nmeth.1444 – volume: 297 start-page: 1160 year: 2002 ident: ref17/cit17 publication-title: Science doi: 10.1126/science.1073765 – volume: 105 start-page: 20221 year: 2008 ident: ref41/cit41 publication-title: Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.0810636105 – volume: 28 start-page: 1918 year: 2003 ident: ref101/cit101 publication-title: Optics Letters doi: 10.1364/OL.28.001918 – volume: 90 start-page: 053902 year: 2007 ident: ref28/cit28 publication-title: Appl. Phys. Lett. doi: 10.1063/1.2437066 – volume: 393 start-page: 1091 year: 2009 ident: ref36/cit36 publication-title: Anal. Bioanal. Chem. doi: 10.1007/s00216-008-2410-4 |
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| SubjectTerms | Collective excitations (including excitons, polarons, plasmons and other charge-density excitations) Condensed matter: electronic structure, electrical, magnetic, and optical properties Cross-disciplinary physics: materials science; rheology Electronic structure and electrical properties of surfaces, interfaces, thin films and low-dimensional structures Exact sciences and technology Gold Imaging Luminescence Materials science Microscopy Nanocrystalline materials Nanorods Nanoscale materials and structures: fabrication and characterization Nanostructure Nanotubes Optical properties and condensed-matter spectroscopy and other interactions of matter with particles and radiation Optical properties of low-dimensional, mesoscopic, and nanoscale materials and structures Photons Physics Surface and interface electron states Three dimensional Tracking |
| Title | Parallel Nanometric 3D Tracking of Intracellular Gold Nanorods Using Multifocal Two-Photon Microscopy |
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