Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients: A Randomized Clinical Trial

The effects of chlorhexidine (CHX) mouthwash, selective oropharyngeal decontamination (SOD), and selective digestive tract decontamination (SDD) on patient outcomes in ICUs with moderate to high levels of antibiotic resistance are unknown. To determine associations between CHX 2%, SOD, and SDD and t...

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Bibliographic Details
Published in:	JAMA : the journal of the American Medical Association Vol. 320; no. 20; p. 2087
Main Authors:	Wittekamp, Bastiaan H, Plantinga, Nienke L, Cooper, Ben S, Lopez-Contreras, Joaquin, Coll, Pere, Mancebo, Jordi, Wise, Matt P, Morgan, Matt P G, Depuydt, Pieter, Boelens, Jerina, Dugernier, Thierry, Verbelen, Valérie, Jorens, Philippe G, Verbrugghe, Walter, Malhotra-Kumar, Surbhi, Damas, Pierre, Meex, Cécile, Leleu, Kris, van den Abeele, Anne-Marie, Gomes Pimenta de Matos, Ana Filipa, Fernández Méndez, Sara, Vergara Gomez, Andrea, Tomic, Viktorija, Sifrer, Franc, Villarreal Tello, Esther, Ruiz Ramos, Jesus, Aragao, Irene, Santos, Claudia, Sperning, Roberta H M, Coppadoro, Patrizia, Nardi, Giuseppe, Brun-Buisson, Christian, Bonten, Marc J M
Format:	Journal Article
Language:	English
Published:	United States 27.11.2018
Subjects:	Adult Aged Aged, 80 and over Anti-Infective Agents - therapeutic use Bacteremia - prevention & control Chlorhexidine - therapeutic use Cross Infection - prevention & control Disinfection - methods Drug Resistance, Bacterial Female Gastrointestinal Tract - microbiology Gram-Negative Bacterial Infections - prevention & control Hospital Mortality Humans Intensive Care Units Male Middle Aged Mouthwashes - therapeutic use Oropharynx - microbiology Respiration, Artificial Young Adult
ISSN:	1538-3598, 1538-3598
Online Access:	Get more information
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