A gadolinium(III) complex of a carboxylic-phosphorus acid derivative of diethylenetriamine covalently bound to inulin, a potential macromolecular MRI contrast agent

A novel conjugate of a polysaccharide and a Gd(III) chelate with potential as contrast agent for magnetic resonance imaging (MRI) was synthesized. The structure of the chelate was derived from H5DTPA by replacing the central pendant arm by a phosphinic acid functional group, which was covalently bou...

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Bibliographic Details

Published in:	Bioconjugate chemistry Vol. 15; no. 4; p. 881
Main Authors:	Lebdusková, Petra, Kotek, Jan, Hermann, Petr, Vander Elst, Luce, Muller, Robert N, Lukes, Ivan, Peters, Joop A
Format:	Journal Article
Language:	English
Published:	United States 01.07.2004
Subjects:	Contrast Media - chemistry Gadolinium - chemistry Inulin - chemistry Ligands Magnetic Resonance Imaging - instrumentation Molecular Structure Organometallic Compounds - chemistry Pentetic Acid - analogs & derivatives Pentetic Acid - chemistry Polyamines - chemistry Protons Spectrum Analysis Water
ISSN:	1043-1802
Online Access:	Get more information
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