Regulation of Selenium Metabolism and Transport

Selenium is regulated in the body to maintain vital selenoproteins and to avoid toxicity. When selenium is limiting, cells utilize it to synthesize the selenoproteins most important to them, creating a selenoprotein hierarchy in the cell. The liver is the central organ for selenium regulation and pr...

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Bibliographic Details
Published in:	Annual review of nutrition Vol. 35; pp. 109 - 134
Main Authors:	Burk, Raymond F, Hill, Kristina E
Format:	Journal Article
Language:	English
Published:	United States 17.07.2015
Subjects:	Animals Biological Availability Biological Transport Biomarkers Diet Dietary Supplements Health Status Homeostasis - physiology Humans Kidney Tubules, Proximal - metabolism LDL-Receptor Related Proteins - physiology Liver - physiology Low Density Lipoprotein Receptor-Related Protein-2 - physiology Nutritional Requirements Organ Specificity Selenium - deficiency Selenium - metabolism Selenium - pharmacokinetics Selenocysteine - metabolism Selenomethionine - metabolism Selenoprotein P - analysis Selenoprotein P - blood Selenoproteins - biosynthesis Selenoproteins - metabolism selenocysteine lyase human selenium metabolism apolipoprotein E receptor-2 selenoprotein hierarchy megalin selenoprotein P
ISSN:	1545-4312
Online Access:	Get more information
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