Multistep Testing Algorithms for Clostridioides difficile Infection

A 10-year-old girl with spina bifida and neurogenic bowel hospitalized for abdominal pain, dehydration, and more than 20 episodes of diarrhea per day. A stool sample test result was positive for Clostridioides difficile by polymerase chain reaction and an enzyme immunoassay result for C difficile to...

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Bibliographic Details
Published in:	JAMA : the journal of the American Medical Association Vol. 330; no. 10; p. 966
Main Authors:	Nicholson, Maribeth R, Donskey, Curtis J
Format:	Journal Article
Language:	English
Published:	United States 12.09.2023
Subjects:	Algorithms Clostridium Infections - diagnosis Diagnosis, Computer-Assisted - methods Humans
ISSN:	1538-3598, 1538-3598
Online Access:	Get more information
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Summary:	A 10-year-old girl with spina bifida and neurogenic bowel hospitalized for abdominal pain, dehydration, and more than 20 episodes of diarrhea per day. A stool sample test result was positive for Clostridioides difficile by polymerase chain reaction and an enzyme immunoassay result for C difficile toxin A and B was negative. How do you interpret these test results?
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1538-3598 1538-3598
DOI:	10.1001/jama.2023.15875