Ultrasensitive quantification of serum vitamin D metabolites using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry

The capacity for quantification of active metabolites of vitamin D (VitD) is highly valuable to evaluate the risks and therapies for numerous diseases such as multiple sclerosis. However, the extremely low circulating levels and poor detectability of some dihydroxyl metabolites such as the 1alpha,25...

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Vydané v:	Analytical chemistry (Washington) Ročník 82; číslo 6; s. 2488
Hlavní autori:	Duan, Xiaotao, Weinstock-Guttman, Bianca, Wang, Hao, Bang, Eunjin, Li, Jun, Ramanathan, Murali, Qu, Jun
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.03.2010
Predmet:	Adult Chromatography, Liquid - methods Female Humans Limit of Detection Male Mass Spectrometry - methods Middle Aged Solid Phase Extraction - methods Vitamin D - blood Vitamin D - metabolism
ISSN:	1520-6882, 1520-6882
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