Fast DNA Sequencing via Transverse Electronic Transport

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of single-stranded DNA while it translocates through a nanopore. Our estima...

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Veröffentlicht in:	Nano letters Jg. 6; H. 4; S. 779 - 782
Hauptverfasser:	Lagerqvist, Johan, Zwolak, Michael, Di Ventra, Massimiliano
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Washington, DC American Chemical Society 01.04.2006
Schlagworte:	Biological and medical sciences Biosensing Techniques - instrumentation Biosensing Techniques - methods Computer Simulation Computer-Aided Design Conformational dynamics in molecular biology DNA - analysis DNA - chemistry DNA - radiation effects Electrochemistry - instrumentation Electrochemistry - methods Electrodes Electron Transport Feasibility Studies Fundamental and applied biological sciences. Psychology Models, Chemical Molecular biophysics Oligonucleotide Array Sequence Analysis - instrumentation Oligonucleotide Array Sequence Analysis - methods Sequence Analysis, DNA - instrumentation Sequence Analysis, DNA - methods Human Nucleotide sequence DNA DNA sequence Nanopore Genome Implementation Nanoporosity
ISSN:	1530-6984, 1530-6992
Online-Zugang:	Volltext
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