Fast DNA Sequencing via Transverse Electronic Transport

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of single-stranded DNA while it translocates through a nanopore. Our estima...

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Vydáno v:	Nano letters Ročník 6; číslo 4; s. 779 - 782
Hlavní autoři:	Lagerqvist, Johan, Zwolak, Michael, Di Ventra, Massimiliano
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Washington, DC American Chemical Society 01.04.2006
Témata:	Biological and medical sciences Biosensing Techniques - instrumentation Biosensing Techniques - methods Computer Simulation Computer-Aided Design Conformational dynamics in molecular biology DNA - analysis DNA - chemistry DNA - radiation effects Electrochemistry - instrumentation Electrochemistry - methods Electrodes Electron Transport Feasibility Studies Fundamental and applied biological sciences. Psychology Models, Chemical Molecular biophysics Oligonucleotide Array Sequence Analysis - instrumentation Oligonucleotide Array Sequence Analysis - methods Sequence Analysis, DNA - instrumentation Sequence Analysis, DNA - methods Human Nucleotide sequence DNA DNA sequence Nanopore Genome Implementation Nanoporosity
ISSN:	1530-6984, 1530-6992
On-line přístup:	Získat plný text
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