Improvement in the Palladium-Catalyzed Miyaura Borylation Reaction by Optimization of the Base: Scope and Mechanistic Study

Aryl boronic acids and esters are important building blocks in API synthesis. The palladium-catalyzed Suzuki-Miyaura borylation is the most common method for their preparation. This paper describes an improvement of the current reaction conditions. By using lipophilic bases such as potassium 2-ethyl...

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Bibliographic Details
Published in:Journal of organic chemistry Vol. 86; no. 1; p. 103
Main Authors: Barroso, Santiago, Joksch, Markus, Puylaert, Pim, Tin, Sergey, Bell, Stephen J, Donnellan, Luke, Duguid, Stewart, Muir, Colin, Zhao, Peichao, Farina, Vittorio, Tran, Duc N, de Vries, Johannes G
Format: Journal Article
Language:English
Published: United States 01.01.2021
ISSN:1520-6904, 1520-6904
Online Access:Get more information
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