MoS2 Quantum Dot@Polyaniline Inorganic-Organic Nanohybrids for in Vivo Dual-Modal Imaging Guided Synergistic Photothermal/Radiation Therapy

In this study, we introduce a versatile nanomaterial based on MoS2 quantum dot@polyaniline (MoS2@PANI) inorganic-organic nanohybrids, which exhibit good potential to not only enhance photoaccoustic (PA) imaging/X-ray computed tomography (CT) signal but also perform efficient radiotherapy (RT)/photot...

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Veröffentlicht in:ACS applied materials & interfaces Jg. 8; H. 37; S. 24331 - 24338
Hauptverfasser: Wang, Jinping, Tan, Xiaoxiao, Pang, Xiaojuan, Liu, Li, Tan, Fengping, Li, Nan
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 21.09.2016
Schlagworte:
dual-modal CT/photoacoustic imaging
polyaniline
MoS2 quantum dots
inorganic−organic nanohybrids
photothermal/radiation therapy
ISSN:1944-8252
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Zusammenfassung:In this study, we introduce a versatile nanomaterial based on MoS2 quantum dot@polyaniline (MoS2@PANI) inorganic-organic nanohybrids, which exhibit good potential to not only enhance photoaccoustic (PA) imaging/X-ray computed tomography (CT) signal but also perform efficient radiotherapy (RT)/photothermal therapy (PTT) of cancer. Upon the intravenous injection of MoS2@PANI hybrid nanoparticles, the in vivo tumor could be precisely positioned and thoroughly eliminated under the PA/CT image-guided combination therapy of PTT/RT. This versatile nanohybrid could show good potential to facilitate simultaneously dual-modal imaging and synergetic PTT/RT to realize better anticancer efficiency.
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ISSN:1944-8252
DOI:10.1021/acsami.6b08391