MoS2 Quantum Dot@Polyaniline Inorganic-Organic Nanohybrids for in Vivo Dual-Modal Imaging Guided Synergistic Photothermal/Radiation Therapy

In this study, we introduce a versatile nanomaterial based on MoS2 quantum dot@polyaniline (MoS2@PANI) inorganic-organic nanohybrids, which exhibit good potential to not only enhance photoaccoustic (PA) imaging/X-ray computed tomography (CT) signal but also perform efficient radiotherapy (RT)/photot...

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Bibliographic Details
Published in:	ACS applied materials & interfaces Vol. 8; no. 37; pp. 24331 - 24338
Main Authors:	Wang, Jinping, Tan, Xiaoxiao, Pang, Xiaojuan, Liu, Li, Tan, Fengping, Li, Nan
Format:	Journal Article
Language:	English
Published:	United States 21.09.2016
Subjects:	dual-modal CT/photoacoustic imaging polyaniline MoS2 quantum dots inorganic−organic nanohybrids photothermal/radiation therapy
ISSN:	1944-8252
Online Access:	Get more information
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Summary:	In this study, we introduce a versatile nanomaterial based on MoS2 quantum dot@polyaniline (MoS2@PANI) inorganic-organic nanohybrids, which exhibit good potential to not only enhance photoaccoustic (PA) imaging/X-ray computed tomography (CT) signal but also perform efficient radiotherapy (RT)/photothermal therapy (PTT) of cancer. Upon the intravenous injection of MoS2@PANI hybrid nanoparticles, the in vivo tumor could be precisely positioned and thoroughly eliminated under the PA/CT image-guided combination therapy of PTT/RT. This versatile nanohybrid could show good potential to facilitate simultaneously dual-modal imaging and synergetic PTT/RT to realize better anticancer efficiency.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1944-8252
DOI:	10.1021/acsami.6b08391