Linezolid Pharmacokinetics in South African Patients with Drug-Resistant Tuberculosis and a High Prevalence of HIV Coinfection

The World Health Organization (WHO) recently recommended that linezolid be prioritized in treatment regimens for drug-resistant tuberculosis (TB), but there are limited data on its pharmacokinetics (PK) in patients with this disease. We conducted an observational study to explore covariate effects o...

Full description

Saved in:

Bibliographic Details
Published in:	Antimicrobial agents and chemotherapy Vol. 63; no. 3
Main Authors:	Wasserman, Sean, Denti, Paolo, Brust, James C M, Abdelwahab, Mahmoud, Hlungulu, Siphokazi, Wiesner, Lubbe, Norman, Jennifer, Sirgel, Frederick A, Warren, Robin M, Esmail, Aliasgar, Dheda, Keertan, Gandhi, Neel R, Meintjes, Graeme, Maartens, Gary
Format:	Journal Article
Language:	English
Published:	United States 01.03.2019
Subjects:	Adult Antitubercular Agents - administration & dosage Antitubercular Agents - pharmacokinetics Antitubercular Agents - therapeutic use Female Humans Linezolid - administration & dosage Linezolid - pharmacokinetics Linezolid - therapeutic use Male Microbial Sensitivity Tests Mycobacterium tuberculosis - drug effects Prospective Studies South Africa Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Pulmonary - drug therapy South Africa linezolid drug-resistant tuberculosis
ISSN:	1098-6596, 1098-6596
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!