T Cell Fate at the Single-Cell Level

T cell responses display two key characteristics. First, a small population of epitope-specific naive T cells expands by several orders of magnitude. Second, the T cells within this proliferating population take on diverse functional and phenotypic properties that determine their ability to exert ef...

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Bibliographic Details
Published in:	Annual review of immunology Vol. 34; pp. 65 - 92
Main Authors:	Buchholz, Veit R, Schumacher, Ton N M, Busch, Dirk H
Format:	Journal Article
Language:	English
Published:	United States 20.05.2016
Subjects:	Adult Stem Cells - immunology Animals Biodiversity Cell Differentiation Cell Lineage Cell Proliferation Cultural Diversity Epitopes, T-Lymphocyte - immunology Epitopes, T-Lymphocyte - metabolism Humans Immunologic Memory Immunotherapy - methods Lymphocyte Activation Single-Cell Analysis - methods T-Lymphocytes - immunology robustness stochasticity T cell differentiation T cell memory immunotherapy stemness
ISSN:	1545-3278
Online Access:	Get more information
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