Organometallic Half-Sandwich Iridium Anticancer Complexes

The low-spin 5d(6) Ir-III organometallic half-sandwich complexes [(eta(5)-Cp-x)Ir(XY)Cl](0/+), Cp-x = Cp*, tetramethyl(phenyl, cyclopentadienyl (Cp-xph), or tetramethyl(biphenyl)-cyclopertadienyl (Cp-xbiph), XY = 1,10-phenanthroline (4-6), 2,2'-bipyridine (7-9), ethylenediamine (10 and 11), or...

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Bibliographic Details
Published in:	Journal of medicinal chemistry Vol. 54; no. 8; pp. 3011 - 3026
Main Authors:	Liu, Zhe, Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, Viktor, Sadler, Peter J.
Format:	Journal Article
Language:	English
Published:	WASHINGTON Amer Chemical Soc 28.04.2011
Subjects:	Cell Line, Tumor Chemistry, Medicinal Drug Screening Assays, Antitumor Female Humans Iridium - chemistry Life Sciences & Biomedicine Models, Molecular Organometallic Compounds - chemistry Organometallic Compounds - pharmacology Pharmacology & Pharmacy Science & Technology (ETA-PENTAMETHYLCYCLOPENTADIENYL)IRIDIUM(III) COMPLEXES RUTHENIUM(II) ARENE COMPLEXES N-HETEROCYCLIC CARBENE MOLECULAR CALCULATIONS CYCLOMETALATED IRIDIUM(III) DNA-BINDING PROPERTIES LIGAND SUBSTITUTION-REACTIONS ANTITUMOR COMPLEXES PLATINUM COMPLEXES METAL-COMPLEXES
ISSN:	0022-2623, 1520-4804, 1520-4804
Online Access:	Get more information
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