Profiling of Histone Post-Translational Modifications in Mouse Brain with High-Resolution Top-Down Mass Spectrometry

As histones play central roles in most chromosomal functions including regulation of DNA replication, DNA damage repair, and gene transcription, both their basic biology and their roles in disease development have been the subject of intense study. Because multiple post-translational modifications (...

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Vydáno v:	Journal of proteome research Ročník 16; číslo 2; s. 599
Hlavní autoři:	Zhou, Mowei, Paša-Tolić, Ljiljana, Stenoien, David L
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 03.02.2017
Témata:	Algorithms Amino Acid Sequence - genetics Animals Brain - metabolism Computational Biology Histones - genetics Histones - metabolism Mass Spectrometry Mice Protein Processing, Post-Translational - genetics Proteome - genetics top-down mass spectrometry histones post-translational modifications
ISSN:	1535-3907, 1535-3907
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