N-Acylsaccharins: Stable Electrophilic Amide-Based Acyl Transfer Reagents in Pd-Catalyzed Suzuki-Miyaura Coupling via N-C Cleavage

The development of efficient catalytic methods for N-C bond cleavage in amides remains an important synthetic challenge. The first Pd-catalyzed Suzuki-Miyaura cross-coupling of N-acylsaccharins with boronic acids by selective N-C bond activation is reported. The reaction enables preparation of a var...

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Bibliographic Details

Published in:	Organic letters Vol. 18; no. 17; p. 4194
Main Authors:	Liu, Chengwei, Meng, Guangrong, Liu, Yongmei, Liu, Ruzhang, Lalancette, Roger, Szostak, Roman, Szostak, Michal
Format:	Journal Article
Language:	English
Published:	United States 02.09.2016
ISSN:	1523-7052, 1523-7052
Online Access:	Get more information
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