Photoinduced Electron Transfer Modulated Photoelectric Signal: Toward an Organic Small Molecule-Based Photoelectrochemical Platform for Formaldehyde Detection
Photoelectrochemical (PEC) sensing has been rapidly evolving in recent years, while the introduction of small molecules with specific recognition functions into the sensing interface remains a nascent area of study. In this work, we reported a PEC biosensor for formaldehyde (FA) detection based on p...
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| Published in: | Analytical chemistry (Washington) Vol. 95; no. 23; p. 9130 |
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| Main Authors: | , , , , , |
| Format: | Journal Article |
| Language: | English |
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13.06.2023
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| ISSN: | 1520-6882, 1520-6882 |
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| Abstract | Photoelectrochemical (PEC) sensing has been rapidly evolving in recent years, while the introduction of small molecules with specific recognition functions into the sensing interface remains a nascent area of study. In this work, we reported a PEC biosensor for formaldehyde (FA) detection based on photoinduced electron transfer (PET)-gated electron injection between organic small molecules and inorganic semiconducting substrates. Specifically, an FA-responsive probe (NA-FA-COOH) and TiO
nanoarrays were integrated to construct a PEC platform (NFC/TiO
) via a coordination bond. NFC served simultaneously as a target-specific recognition element and a modulator of photoinduced electron injection. Treatment of NFC/TiO
by FA would suppress the intramolecular PET process, with the quenched photocurrent signal due to the changed carrier transfer pathway, thus establishing the PEC platform for FA based on effective PET modulation. The proposed PEC system exhibited high selectivity and sensitivity, with a low detection limit of 0.071 μM. This study presents a novel perspective on the use of organic small molecules with a PET effect for advanced PEC bioanalysis. |
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| AbstractList | Photoelectrochemical (PEC) sensing has been rapidly evolving in recent years, while the introduction of small molecules with specific recognition functions into the sensing interface remains a nascent area of study. In this work, we reported a PEC biosensor for formaldehyde (FA) detection based on photoinduced electron transfer (PET)-gated electron injection between organic small molecules and inorganic semiconducting substrates. Specifically, an FA-responsive probe (NA-FA-COOH) and TiO
nanoarrays were integrated to construct a PEC platform (NFC/TiO
) via a coordination bond. NFC served simultaneously as a target-specific recognition element and a modulator of photoinduced electron injection. Treatment of NFC/TiO
by FA would suppress the intramolecular PET process, with the quenched photocurrent signal due to the changed carrier transfer pathway, thus establishing the PEC platform for FA based on effective PET modulation. The proposed PEC system exhibited high selectivity and sensitivity, with a low detection limit of 0.071 μM. This study presents a novel perspective on the use of organic small molecules with a PET effect for advanced PEC bioanalysis. Photoelectrochemical (PEC) sensing has been rapidly evolving in recent years, while the introduction of small molecules with specific recognition functions into the sensing interface remains a nascent area of study. In this work, we reported a PEC biosensor for formaldehyde (FA) detection based on photoinduced electron transfer (PET)-gated electron injection between organic small molecules and inorganic semiconducting substrates. Specifically, an FA-responsive probe (NA-FA-COOH) and TiO2 nanoarrays were integrated to construct a PEC platform (NFC/TiO2) via a coordination bond. NFC served simultaneously as a target-specific recognition element and a modulator of photoinduced electron injection. Treatment of NFC/TiO2 by FA would suppress the intramolecular PET process, with the quenched photocurrent signal due to the changed carrier transfer pathway, thus establishing the PEC platform for FA based on effective PET modulation. The proposed PEC system exhibited high selectivity and sensitivity, with a low detection limit of 0.071 μM. This study presents a novel perspective on the use of organic small molecules with a PET effect for advanced PEC bioanalysis.Photoelectrochemical (PEC) sensing has been rapidly evolving in recent years, while the introduction of small molecules with specific recognition functions into the sensing interface remains a nascent area of study. In this work, we reported a PEC biosensor for formaldehyde (FA) detection based on photoinduced electron transfer (PET)-gated electron injection between organic small molecules and inorganic semiconducting substrates. Specifically, an FA-responsive probe (NA-FA-COOH) and TiO2 nanoarrays were integrated to construct a PEC platform (NFC/TiO2) via a coordination bond. NFC served simultaneously as a target-specific recognition element and a modulator of photoinduced electron injection. Treatment of NFC/TiO2 by FA would suppress the intramolecular PET process, with the quenched photocurrent signal due to the changed carrier transfer pathway, thus establishing the PEC platform for FA based on effective PET modulation. The proposed PEC system exhibited high selectivity and sensitivity, with a low detection limit of 0.071 μM. This study presents a novel perspective on the use of organic small molecules with a PET effect for advanced PEC bioanalysis. |
| Author | Gao, Yuan Huang, Lingting Yu, Zhichao Tang, Dianping Zeng, Yongyi Liu, Xiaolong |
| Author_xml | – sequence: 1 givenname: Yuan surname: Gao fullname: Gao, Yuan organization: Key Laboratory of Analytical Science for Food Safety and Biology (MOE & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China – sequence: 2 givenname: Zhichao surname: Yu fullname: Yu, Zhichao organization: Key Laboratory of Analytical Science for Food Safety and Biology (MOE & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China – sequence: 3 givenname: Lingting surname: Huang fullname: Huang, Lingting organization: Key Laboratory of Analytical Science for Food Safety and Biology (MOE & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China – sequence: 4 givenname: Yongyi orcidid: 0000-0001-7441-4271 surname: Zeng fullname: Zeng, Yongyi organization: The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China – sequence: 5 givenname: Xiaolong orcidid: 0000-0002-3096-4981 surname: Liu fullname: Liu, Xiaolong organization: The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China – sequence: 6 givenname: Dianping orcidid: 0000-0002-0134-3983 surname: Tang fullname: Tang, Dianping organization: Key Laboratory of Analytical Science for Food Safety and Biology (MOE & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37249157$$D View this record in MEDLINE/PubMed |
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| Title | Photoinduced Electron Transfer Modulated Photoelectric Signal: Toward an Organic Small Molecule-Based Photoelectrochemical Platform for Formaldehyde Detection |
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