Toward Synthetic Intrinsically Disordered Polypeptides (IDPs): Controlled Incorporation of Glycine in the Ring-Opening Polymerization of N -Carboxyanhydrides

Intrinsically disordered proteins (IDPs) do not have a well-defined folded structure but instead behave as extended polymer chains in solution. Many IDPs are rich in glycine residues, which create steric barriers to secondary structuring and protein folding. Inspired by this feature, we have studied...

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Bibliographic Details
Published in:Biomacromolecules Vol. 25; no. 5; p. 3033
Main Authors: Badreldin, Mostafa, Salas-Ambrosio, Pedro, Bourasseau, Sylvain, Lecommandoux, Sebastien, Harrisson, Simon, Bonduelle, Colin
Format: Journal Article
Language:English
Published: United States 13.05.2024
ISSN:1526-4602, 1526-4602
Online Access:Get more information
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