Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach

Commonly used non-antibiotic drugs have been associated with changes in gut microbiome composition, paving the way for the possibility of repurposing FDA-approved molecules as next-generation microbiome therapeutics. Herein, we developed and validated an high-throughput screening platform─the mini g...

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Vydané v:	Journal of medicinal chemistry Ročník 64; číslo 23; s. 17277
Hlavní autori:	Barone, Monica, Rampelli, Simone, Biagi, Elena, Bertozzi, Sine Mandrup, Falchi, Federico, Cavalli, Andrea, Armirotti, Andrea, Brigidi, Patrizia, Turroni, Silvia, Candela, Marco
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 09.12.2021
Predmet:	Drug Repositioning Gastrointestinal Microbiome - drug effects Gene Expression Profiling High-Throughput Screening Assays Humans Validation Studies as Topic
ISSN:	1520-4804, 1520-4804
On-line prístup:	Zistit podrobnosti o prístupe
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