Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins

Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) regulates several key physiological and pathophysiological processes, and its dysregulation has been implicated in obesity, diabetes, and cancer. CaMKK2 is inhibited through phosphorylation in a process involving binding to the scaffolding 1...

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Bibliographic Details
Published in:ACS chemical biology Vol. 15; no. 11; p. 3060
Main Authors: Lentini Santo, Domenico, Petrvalska, Olivia, Obsilova, Veronika, Ottmann, Christian, Obsil, Tomas
Format: Journal Article
Language:English
Published: 20.11.2020
ISSN:1554-8937, 1554-8937
Online Access:Get more information
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