Exhaustively Identifying Cross-Linked Peptides with a Linear Computational Complexity

Chemical cross-linking coupled to mass spectrometry is a powerful tool to study protein-protein interactions and protein conformations. Two linked peptides are ionized and fragmented to produce a tandem mass spectrum. In such an experiment, a tandem mass spectrum contains ions from two peptides. The...

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Bibliographic Details

Published in:	Journal of proteome research Vol. 16; no. 10; p. 3942
Main Authors:	Yu, Fengchao, Li, Ning, Yu, Weichuan
Format:	Journal Article
Language:	English
Published:	United States 06.10.2017
Subjects:	Algorithms Cross-Linking Reagents - chemistry Databases, Protein Humans Peptides - chemistry Protein Conformation Protein Interaction Maps - genetics Proteins - chemistry Proteomics Software Tandem Mass Spectrometry linear computational complexity exhaustive database search cross-linked peptides identification
ISSN:	1535-3907, 1535-3907
Online Access:	Get more information
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