Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase

The aim of the present study was to investigate possible mechanisms that could be involved in the deactivation of the assembled, catalytically active NADPH oxidase of phagocytic cells and thereby lead to termination of O(2)(.-) production. Our major findings are the following: (1) Addition of GDP to...

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Bibliographic Details

Published in:	Biochemistry (Easton) Vol. 41; no. 34; p. 10710
Main Authors:	Moskwa, Patryk, Dagher, Marie-Claire, Paclet, Marie-Hélène, Morel, Francoise, Ligeti, Erzsébet
Format:	Journal Article
Language:	English
Published:	United States 27.08.2002
Subjects:	Catalysis - drug effects Enzyme Activation - drug effects Guanosine Diphosphate - metabolism Guanosine Diphosphate - pharmacology Guanosine Triphosphate - metabolism Humans NADPH Oxidases - antagonists & inhibitors NADPH Oxidases - metabolism Neutrophils - enzymology Phagocytosis Phosphoproteins - metabolism rac GTP-Binding Proteins - metabolism
ISSN:	0006-2960
Online Access:	Get more information
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