Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase

The aim of the present study was to investigate possible mechanisms that could be involved in the deactivation of the assembled, catalytically active NADPH oxidase of phagocytic cells and thereby lead to termination of O(2)(.-) production. Our major findings are the following: (1) Addition of GDP to...

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Vydané v:	Biochemistry (Easton) Ročník 41; číslo 34; s. 10710
Hlavní autori:	Moskwa, Patryk, Dagher, Marie-Claire, Paclet, Marie-Hélène, Morel, Francoise, Ligeti, Erzsébet
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 27.08.2002
Predmet:	Catalysis - drug effects Enzyme Activation - drug effects Guanosine Diphosphate - metabolism Guanosine Diphosphate - pharmacology Guanosine Triphosphate - metabolism Humans NADPH Oxidases - antagonists & inhibitors NADPH Oxidases - metabolism Neutrophils - enzymology Phagocytosis Phosphoproteins - metabolism rac GTP-Binding Proteins - metabolism
ISSN:	0006-2960
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