Synthesis and Bioactivity of Reduced Chalcones Containing Sulfonamide Side Chains

The effect on the bioactivity of antibacterial sulfonamide drugs against malaria and tuberculosis via an increase of the lipid solubility groups by condensation with a reduced chalcone was investigated. Sulfonamide derivatives (8a-8d) were obtained via a 1,3-diarylpropane scaffold, prepared by reduc...

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Bibliographic Details

Published in:	Journal of natural products (Washington, D.C.) Vol. 81; no. 1; pp. 41 - 48
Main Authors:	Noreljaleel, Anwar E. M., Wilhelm, A., Bonnet, S. L., van der Westhuizen, J. H.
Format:	Journal Article
Language:	English
Published:	WASHINGTON Amer Chemical Soc 26.01.2018
Subjects:	Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Plant Sciences Science & Technology MALARIA INHIBITION ANTIBACTERIAL ACTIVITY DERIVATIVES TUBERCULOSIS
ISSN:	0163-3864, 1520-6025, 1520-6025
Online Access:	Get more information
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