Small Molecular Antibacterial Peptoid Mimics: The Simpler the Better

The emergence of multidrug resistant bacteria compounded by the depleting arsenal of antibiotics has accelerated efforts toward development of antibiotics with novel mechanisms of action. In this report, we present a series of small molecular antibacterial peptoid mimics which exhibit high in vitro...

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Bibliographic Details
Published in:	Journal of medicinal chemistry Vol. 57; no. 4; pp. 1428 - 1436
Main Authors:	Ghosh, Chandradhish, Manjunath, Goutham B., Akkapeddi, Padma, Yarlagadda, Venkateswarlu, Hoque, Jiaul, Uppu, Divakara S. S. M., Konai, Mohini M., Haldar, Jayanta
Format:	Journal Article
Language:	English
Published:	WASHINGTON Amer Chemical Soc 27.02.2014
Subjects:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Chemistry, Medicinal Chromatography, High Pressure Liquid Drug Resistance, Microbial Enterococcus faecium - drug effects Hemolysis - drug effects Life Sciences & Biomedicine Magnetic Resonance Spectroscopy Mass Spectrometry Methicillin-Resistant Staphylococcus aureus - drug effects Microbial Sensitivity Tests Microscopy, Electron, Scanning Microscopy, Fluorescence Molecular Mimicry Peptoids - chemistry Peptoids - pharmacology Pharmacology & Pharmacy Science & Technology Spectrophotometry, Ultraviolet HOST-DEFENSE PEPTIDES POLYMERS HELICAL ANTIMICROBIAL PEPTIDES BACTERIA PEPTIDOMIMETICS DE-NOVO DESIGN SYNTHETIC MIMICS AMPHIPHILICITY DERIVATIVES INFECTIOUS-DISEASES SOCIETY
ISSN:	0022-2623, 1520-4804, 1520-4804
Online Access:	Get more information
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