An Information Technology Framework for Predictive, Preventive and Personalised Medicine A Use-Case with Hepatocellular Carcinoma

This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose...

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Bibliographic Details
Main Authors: Berliner, Leonard, Lemke, Heinz U
Format: eBook
Language:English
Published: Cham Springer International Publishing AG 2015
Springer International Publishing
Springer
Edition:1
Series:Advances in Predictive, Preventive and Personalised Medicine
Subjects:
Data Mining and Knowledge Discovery
Health Informatics
Hepatology
Liver
Medicine
Medicine & Public Health
Medicine, Preventive
Oncology
Personalized medicine
Simulation and Modeling
ISBN:3319121650, 9783319121659
ISSN:2211-3495, 2211-3509
Online Access:Get full text
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Summary:This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.
ISBN:3319121650
9783319121659
ISSN:2211-3495
2211-3509
DOI:10.1007/978-3-319-12166-6