Catalytic and Atom-Economic Intermolecular Amidoselenenylation of Alkenes

A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides i...

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Bibliographic Details
Published in:Organic letters Vol. 18; no. 2; pp. 176 - 179
Main Authors: Tang, E., Wang, Weilin, Zhao, Yinjiao, Zhang, Meng, Dai, Xin
Format: Journal Article
Language:English
Published: WASHINGTON Amer Chemical Soc 15.01.2016
Subjects:
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
TETHERED ALKENES
ORGANOSELENIUM
SOLID-PHASE SYNTHESIS
DIPHENYL DISELENIDE
GLUTATHIONE-PEROXIDASE
MOUSE MODEL
CHEMISTRY
INTRAMOLECULAR SELENO-ARYLATION
COUMARINS
AMIDES
ISSN:1523-7060, 1523-7052, 1523-7052
Online Access:Get more information
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Summary:A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides in good yield and with high regioselectivity and diastereoselectivity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1523-7060
1523-7052
1523-7052
DOI:10.1021/acs.orglett.5b03157