Catalytic and Atom-Economic Intermolecular Amidoselenenylation of Alkenes

A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides i...

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Veröffentlicht in:Organic letters Jg. 18; H. 2; S. 176 - 179
Hauptverfasser: Tang, E., Wang, Weilin, Zhao, Yinjiao, Zhang, Meng, Dai, Xin
Format: Journal Article
Sprache:Englisch
Veröffentlicht: WASHINGTON Amer Chemical Soc 15.01.2016
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ISSN:1523-7060, 1523-7052, 1523-7052
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Abstract A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides in good yield and with high regioselectivity and diastereoselectivity.
AbstractList A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides in good yield and with high regioselectivity and diastereoselectivity.A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides in good yield and with high regioselectivity and diastereoselectivity.
A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides in good yield and with high regioselectivity and diastereoselectivity.
Author Zhao, Yinjiao
Dai, Xin
Wang, Weilin
Zhang, Meng
Tang, E.
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  organization: Yunnan Univ, Sch Chem Sci & Technol, 2 Green Lake North Rd, Kunming 650091, Peoples R China
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Issue 2
Keywords TETHERED ALKENES
ORGANOSELENIUM
SOLID-PHASE SYNTHESIS
DIPHENYL DISELENIDE
GLUTATHIONE-PEROXIDASE
MOUSE MODEL
CHEMISTRY
INTRAMOLECULAR SELENO-ARYLATION
COUMARINS
AMIDES
Language English
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PublicationTitle Organic letters
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PublicationYear 2016
Publisher Amer Chemical Soc
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Snippet A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and...
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SubjectTerms Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
Title Catalytic and Atom-Economic Intermolecular Amidoselenenylation of Alkenes
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