Base-Dependent Divergent Annulation of 4-Chloro-3-formylcoumarin and Tetrahydroisoquinoline: Application to the Synthesis of Isolamellarins and Hydroxypyrrolones

A series of pyrrolo[2,1-a]isoquinoline and coumarin-fused pentacyclic derivatives were synthesized via base-mediated divergent annulation of 4-chloro-3-formylcoumarin and tetrahydroisoquinoline as a key step. This method was then extended to the preparation of isolamellarins A and B (isolamellarin G...

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Vydané v:	Journal of organic chemistry Ročník 84; číslo 6; s. 3662 - 3670
Hlavní autori:	Vyasamudri, Sameer, Yang, Ding-Yah
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	WASHINGTON Amer Chemical Soc 15.03.2019
Predmet:	Chemistry Chemistry, Organic Physical Sciences Science & Technology LAMELLARIN-ALPHA 20-SULFATE CHILENINE INHIBITORS DERIVATIVES ALKALOIDS
ISSN:	0022-3263, 1520-6904, 1520-6904
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