IceCoder: Identification of Ice Phases in Molecular Simulation Using Variational Autoencoder

The identification and classification of different phases of ice within molecular simulations are challenging tasks due to the complex and varied phase space of ice, which includes numerous crystalline and amorphous forms. Traditional order parameters often struggle to differentiate between these ph...

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Vydané v:Journal of chemical theory and computation Ročník 21; číslo 4; s. 1916
Hlavní autori: Maity, Dibyendu, Chakrabarty, Suman
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 25.02.2025
ISSN:1549-9626, 1549-9626
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Shrnutí:The identification and classification of different phases of ice within molecular simulations are challenging tasks due to the complex and varied phase space of ice, which includes numerous crystalline and amorphous forms. Traditional order parameters often struggle to differentiate between these phases, especially under the conditions of thermal fluctuations. In this work, we present a novel machine learning-based framework, , which combines a variational autoencoder (VAE) with the smooth overlap of atomic position (SOAP) descriptor to classify a large number of ice phases effectively. Our approach compresses high-dimensional SOAP vectors into a two-dimensional latent space using VAE, facilitating the visualization and distinction of various ice phases. We trained the model on a comprehensive data set generated through molecular dynamics simulations and demonstrated its ability to accurately detect various phases of crystalline ice as well as liquid water at the molecular level. IceCoder provides a robust and generalizable tool for tracking ice phase transitions in simulations, overcoming the limitations of traditional methods. This approach may also be generalized to detect polymorphs in other molecular crystals, leading to new insights into the microscopic mechanisms underlying nucleation, growth, and phase transitions while maintaining computational efficiency.
Bibliografia:ObjectType-Article-1
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ISSN:1549-9626
1549-9626
DOI:10.1021/acs.jctc.4c01298