Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting

Glioblastoma multiforme (GBM) is a highly lethal and aggressive tumor of the brain that carries a poor prognosis. Temozolomide (TMZ) has been widely used as a first-line treatment for GBM. However, poor brain targeting, side effects, and drug resistance limit its application for the treatment of GBM...

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Vydané v:	Molecular pharmaceutics Ročník 18; číslo 3; s. 915
Hlavní autori:	Wang, Liangxiao, Tang, Shengnan, Yu, Yawen, Lv, Yanan, Wang, Aiping, Yan, Xiuju, Li, Nuannuan, Sha, Chunjie, Sun, Kaoxiang, Li, Youxin
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.03.2021
Predmet:	anti-EphA3 glioblastoma Temozolomide gold nanoparticles intranasal administration
ISSN:	1543-8392, 1543-8392
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