Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting

Glioblastoma multiforme (GBM) is a highly lethal and aggressive tumor of the brain that carries a poor prognosis. Temozolomide (TMZ) has been widely used as a first-line treatment for GBM. However, poor brain targeting, side effects, and drug resistance limit its application for the treatment of GBM...

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Veröffentlicht in:	Molecular pharmaceutics Jg. 18; H. 3; S. 915
Hauptverfasser:	Wang, Liangxiao, Tang, Shengnan, Yu, Yawen, Lv, Yanan, Wang, Aiping, Yan, Xiuju, Li, Nuannuan, Sha, Chunjie, Sun, Kaoxiang, Li, Youxin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.2021
Schlagworte:	anti-EphA3 glioblastoma Temozolomide gold nanoparticles intranasal administration
ISSN:	1543-8392, 1543-8392
Online-Zugang:	Weitere Angaben
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