Malondialdehyde-Induced Post-translational Modifications in Hemoglobin of Smokers by NanoLC-NSI/MS/MS Analysis

Malondialdehyde (MDA) is the most abundant α,β-unsaturated aldehyde generated from endogenous peroxidation of polyunsaturated fatty acids and is present in cigarette smoke. Post-translational modifications of blood hemoglobin can serve as biomarkers for exposure to chemicals. In this study, two type...

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Veröffentlicht in:	Journal of proteome research Jg. 21; H. 12; S. 2947
Hauptverfasser:	Chen, Hauh-Jyun Candy, Chen, Chau-Yi, Fang, Ya-Hsuan, Hung, Kai-Wei, Wu, Deng-Chyang
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 02.12.2022
Schlagworte:	Biomarkers - metabolism Hemoglobins - chemistry Humans Lysine - metabolism Malondialdehyde Protein Processing, Post-Translational Smokers Tandem Mass Spectrometry posttranslational modifications malondialdehyde biomarker selected reaction monitoring hemoglobin smoking
ISSN:	1535-3907, 1535-3907
Online-Zugang:	Weitere Angaben
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