Long-Acting Efavirenz and HIV-1 Fusion Inhibitor Peptide Co-loaded Polymer-Lipid Hybrid Nanoparticles: Statistical Optimization, Cellular Uptake, and In Vivo Biodistribution

The objective of the present study was to develop long-acting efavirenz (Efa)-enfuvirtide (Enf) Co-loaded polymer-lipid hybrid nanoparticles (PLN) with improved intracellular delivery to target T-cells and macrophage cells located in multiple human immunodeficiency virus sanctuaries. The Box-Behnken...

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Bibliographic Details
Published in:Molecular pharmaceutics Vol. 17; no. 10; p. 3990
Main Authors: Surve, Dhanashree H, Jirwankar, Yugandhara B, Dighe, Vikas D, Jindal, Anil B
Format: Journal Article
Language:English
Published: 05.10.2020
ISSN:1543-8392, 1543-8392
Online Access:Get more information
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