Direct Reprogramming of Mouse Fibroblasts to Osteoblast-like Cells Using Runx2/Dlx5 Factors on Engineered Stiff Hydrogels

Direct reprogramming of somatic cells into functional cells still faces major limitations in terms of efficiency and achieving functional maturity of the reprogramed cells. While different approaches have been developed commonly based on exploiting biochemical signals, introducing appropriate mechan...

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Veröffentlicht in:	ACS applied materials & interfaces Jg. 15; H. 51; S. 59209
Hauptverfasser:	Zhang, Junwei, Wang, Yao, Guo, Jing, Zhang, Nihui, He, Jing, Zhou, Zongke, Wu, Fang
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 27.12.2023
Schlagworte:	mechanical microenvironment transcriptional factors reprogramming efficiency cell therapy direct reprogramming
ISSN:	1944-8252, 1944-8252
Online-Zugang:	Weitere Angaben
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