Construction of 5-Amino-1,2-Selenazole Scaffolds through N-Selenocyanation/Cyclization of Enaminones Using KSeCN

A metal-free and mild approach for constructing 5-amino-1,2-selenazole skeletons by NBS/KSeCN-mediated N-selenocyanation and nucleophilic cyclization of beta-enaminones has been developed. Various isoselenazole compounds and the isoselenazolyl derivatives of anti-inflammatory medicines, including is...

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Bibliographic Details

Published in:	Organic letters Vol. 26; no. 23; pp. 4992 - 4997
Main Authors:	Yuan, Caifeng, Huang, Xuankun, Guo, Jianhua, Shen, Yiwen, Shang, Na, Tang, Qilin, Yang, Jing, Huang, Yi, Zhang, Hongbin, Tang, E.
Format:	Journal Article
Language:	English
Published:	WASHINGTON Amer Chemical Soc 14.06.2024
Subjects:	Chemistry Chemistry, Organic Physical Sciences Science & Technology TARGET THIAZYL RADICALS MECHANISM THIOREDOXIN SUBSTRATE ORGANOSELENIUM COMPOUNDS ISOTHIAZOLES EBSELEN ISOSELENAZOLES DERIVATIVES
ISSN:	1523-7060, 1523-7052, 1523-7052
Online Access:	Get more information
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