Methods for Analysing and Reporting EQ-5D Data

This open access book is the first published guide about how to analyse data produced by the EQ-5D, one of the most widely used Patient Reported Outcomes questionnaires world wide. The authors provide practical, clear and comprehensive guidance in five concise chapters. Following an overview of the...

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Hlavní autoři: Devlin, Nancy, Parkin, David, Janssen, Bas
Médium: E-kniha
Jazyk:angličtina
Vydáno: Cham Springer International Publishing AG 2020
Springer Nature
Vydání:1
Edice:Open Access
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ISBN:3030476219, 9783030476212, 9783030476229, 3030476227
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Obsah:
  • 4.2 Positive and Normative Considerations in Choice of Value Set -- 4.3 Simple Descriptive Statistics and Inference -- 4.4 Examining the Distribution of the EQ-5D Values -- 4.5 Variance and Heteroskedasticity -- 4.6 Exploring Clusters in EQ-5D Value Distributions -- 4.7 Regression Analysis -- 4.8 Uncertainty and Sensitivity Analysis -- References -- 5 Advanced Topics -- 5.1 Analysing Changes and Differences in EQ-5D Values and EQ VAS Scores -- 5.1.1 Defining the Outcome of an Intervention Study as a Change -- 5.1.2 Minimal Important Differences (MIDs) -- 5.1.3 Case-Mix and Risk Adjustment of EQ-5D Data -- 5.2 Mapping -- References -- Glossary of EQ-5D Terms
  • Intro -- Foreword By Niek Klazinga -- Foreword By Elly Stolk and Gouke Bonsel -- Preface -- Acknowledgements -- Contents -- About the Authors -- 1 An Introduction to EQ-5D Instruments and Their Applications -- 1.1 Measuring Health Using the EQ-5D -- 1.2 What does the EQ-5D Measure? -- 1.2.1 The EQ-5D Profile -- 1.2.2 EQ VAS -- 1.2.3 EQ-5D Values -- 1.2.4 Which Aspect of the Information Provided by the EQ-5D Should be the Primary Focus of My Analysis? -- 1.3 EQ-5D Data Collection and Data Handling -- 1.4 Before Starting Your Analysis -- 1.4.1 Treatment of Missing Data-What to Do, What Not to Do -- 1.4.2 Planning Your Analysis -- 1.5 Guide to the Rest of this Book -- References -- 2 Analysis of EQ-5D Profiles -- 2.1 Cross-Sectional Analysis: Describing Health at a Point in Time by Dimension and Level -- 2.2 Longitudinal Analysis: Describing Changes in Health Between Two Time Points by Dimension and Level -- 2.3 Cross-Sectional Analysis: Describing Health at a Point in Time Using Profiles -- 2.4 Longitudinal Analysis: Describing Changes in Health Between Two Time Points Using Profiles -- 2.4.1 The Paretian Classification of Health Change (PCHC) -- 2.4.2 The Probability of Superiority -- 2.4.3 Health Profile Grid (HPG) -- 2.5 Summarising the Severity of EQ-5D Profiles -- 2.5.1 The Level Sum Score (LSS) -- 2.5.2 The Level Frequency Score (LFS) -- 2.6 Analysing the Informativity of EQ-5D Profile Data -- 2.6.1 Shannon Indices -- 2.6.2 Health State Density Curve (HSDC) -- 2.6.3 Health State Density Index (HSDI) and Other Related Indices -- Appendix: Analysis of the LFS for the EQ-5D-5L -- References -- 3 Analysis of EQ VAS Data -- 3.1 Interpreting the EQ VAS -- 3.2 Simple Descriptive Statistics and Inference -- 3.3 Modelling Determinants of EQ VAS Scores -- References -- 4 Analysis of EQ-5D Values -- 4.1 Value Sets and Their Properties