Use of Peptide Microarrays for Fast and Informative Profiling of Therapeutic Antibody Formulation Conditions

Methods to optimize the solution behavior of therapeutic proteins are frequently time-consuming, provide limited information, and often use milligram quantities of material. Here, we present a simple, versatile method that provides valuable information to guide the identification and comparison of f...

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Bibliographic Details
Published in:	Molecular pharmaceutics Vol. 18; no. 11; p. 4131
Main Authors:	Austerberry, James, Edwards, John, Eyes, Tim, Derrick, Jeremy P
Format:	Journal Article
Language:	English
Published:	United States 01.11.2021
Subjects:	Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - therapeutic use Biological Products - chemistry Biological Products - therapeutic use Chemistry, Pharmaceutical - methods Humans Machine Learning Peptides - chemistry Protein Array Analysis - methods Protein Stability Single-Chain Antibodies - chemistry Single-Chain Antibodies - therapeutic use formulation microarray peptide biopharmaceutical monoclonal antibody
ISSN:	1543-8392, 1543-8392
Online Access:	Get more information
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